CLIMEN Tablet Ref.[50748] Active ingredients: Cyproterone Estradiol

Source: Web Search  Revision Year: 2009  Publisher: Bayer Pharma AG Germany.

4.1. Therapeutic indications

CLIMEN coated tablet is indicated for the prevention of menopause-related osteoporosis in women with increased risk of fracture and who do not tolerate, or who are contraindicated for other treatments for the prevention of osteoporosis.

Consult with your doctor before you decide to take this treatment.

Only limited data are available as regards treatment in women aged 65 and over.

4.2. Posology and method of administration

Mode of administration

Taken orally.

Dosage

This treatment consists of 1 tablet per day for 21 days, to be taken without interruption in the following order: take 1 white tablet each day for 11 days, then 1 pink tablet each day for the next 10 days. You will then observe a 7-day break in pill taking.

You can start the treatment on any day you wish. However, if you are changing over from a sequential hormone replacement therapy to CLIMEN, it is recommended that you start your treatment after bleeding has stopped, that is to say the day you would have started a new treatment cycle of your sequential hormone therapy.

You may experience menstrual-like bleeding during the break in taking pills.

This bleeding is normal and slight in nature.

If heavy or irregular bleeding occurs, consult your doctor. Carefully detach the disk calendar. Adhere it to the beige disk of the blister pack and position the day of your first pill directly under the beige compartment marked “start”. For example, if you take your first pill on a Monday you adhere the disk calendar to the blister pack in such a way that ‘Mon’ appears just below the beige compartment marked ‘start’.

This will ensure that you are taking CLIMEN as directed.

1st Day: Start the blister pack by taking the white tablet from the ‘start’ compartment.

Following days: Take the subsequent tablets in the order indicated by the arrows.

Next blister packs: After a break of 7 days, you will start your next blister pack regardless of the actual date of any possible menstruation. For example, if you started your first blister pack on a Monday, you should also start the subsequent blister packs on a Monday, even if your are still menstruating.

In any case, you should always strictly follow the prescribed regimen.

Consult your doctor of pharmacist if you think the effect of CLIMEN coated tablet is either too strong or too weak.

4.9. Overdose

Signs of overdose generally include a sensation of pain in the breast area, swollen stomach, flatulence, nausea, vomiting, irritability, bleeding. No specific treatment is necessary in such cases. Ask your doctor for advice if any of these symptoms persist.

6.3. Shelf life

Do not use CLIMEN coated tablets after the expiration date printed on the box.

6.4. Special precautions for storage

Store below +30°C.

Keep away from, and out of sight of children.

6.5. Nature and contents of container

This medication is available as a coated tablet. Each box contains 21 tablets.

6.6. Special precautions for disposal and other handling

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

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