COLDKRIS Capsule Ref.[115642] Active ingredients: Chlorphenamine

Source: Registered Drug Product Database (NG)  Publisher: Krishat Pharma Industries Limited, KM 15, Lagos-Ibadan Expressway, Ibadan, Oyo State, NIGERIA, Email: info@krishatpharma.com, Company contacts details: operations@krishatpharma.com

4.1. Therapeutic indications

The symptomatic control of allergic conditions which respond to antihistamines including hay fever, urticaria, vasomotor rhinitis, food allergy, drug and serum reactions, pruritus vulvae, pruritus ani, and insect bites.

4.2. Posology and method of administration

The route of administration for chlorphenamine capsule is oral.

Adults and the elderly: 4 mg every 4–6 hours (maximum of 24mg daily).

Not recommended for use in children below 12 years of age.

Or as directed by the physician.

Method of administration

Oral Capsule.

4.9. Overdose

Symptoms and signs

The estimated lethal dose of chlorphenamine is 25 to 50 mg/kg body weight. Symptoms and signs include sedation, paradoxical excitation of the CNS, toxic psychosis, convulsions, apnoea, anticholinergic effects, dystonic reactions and cardiovascular collapse including arrhythmias.

Treatment

Symptomatic and supportive measures should be provided with special attention to cardiac, respiratory, renal and hepatic functions and fluid and electrolyte balance. If overdosage is by the oral route, treatment with activated charcoal should be considered provided there are no contraindications for use and the overdose has been taken recently (treatment is most effective if given within an hour of ingestion). Treat hypotension and arrhythmias vigorously. CNS convulsions may be treated with i.v. diazepam.

Haemoperfusion may be used in severe cases.

6.3. Shelf life

36 months.

6.4. Special precautions for storage

Store below 30°C, protect from light and moisture.

KEEP OUT OF REACH OF CHILDREN.

6.5. Nature and contents of container

10 capsule PVC/ALU blister Pack & 10 Blister pack in a monocarton (100 capsules).

6.6. Special precautions for disposal and other handling

No special requirements.

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