Source: FDA, National Drug Code (US) Revision Year: 2020
FOR DIAGNOSTIC USE ONLY
CORTROSYN (cosyntropin) for Injection is a sterile lyophilized powder in vials containing 0.25 mg of CORTROSYN and 10 mg of mannitol to be reconstituted with 1 mL of 0.9% Sodium Chloride Injection, USP. Administration is by intravenous or intramuscular injection. Cosyntropin is a 1–24 corticotropin, a synthetic subunit of ACTH. It is an open chain polypeptide containing, from the N terminus, the first 24 of the 39 amino acids of natural ACTH.
The sequence of amino acids in the 1–24 compound is as follows:
| Ser | Tyr | Ser | Met | Glu | His | Phe | Arg | Trp | Gly | Lys |
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 |
| Pro | Val | Gly | Lys | Lys | Arg | Arg | Pro | Val | Lys | Val |
| 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 |
| Tyr | Pro | |||||||||
| 23 | 24 |
| How Supplied |
|---|
|
Box of 10 vials of CORTROSYN (cosyntropin) for Injection 0.25 mg Amphastar Pharmaceuticals, Inc., Rancho Cucamonga, CA 91730 U.S.A., REV. 9-10 |
| Drug | Countries | |
|---|---|---|
| CORTROSYN | Canada, Japan, United States |
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