DAFLON Film-coated tablet Ref.[50939] Active ingredients: Diosmin Hesperidin

Source: Marketing Authorisation Holder  Revision Year: 2019  Publisher: Les Laboratoires Servier France.

Product name and form

DAFLON 500 mg, film-coated tablet.

Pharmaceutical Form

Film-coated tablet.

Qualitative and quantitative composition

Micronised purified flavonoid fraction: 500 mg

Corresponding to:

Diosmin: 90 per cent: 450 mg
Flavonoids expressed as hesperidin: 10 per cent: 50 mg
Mean humidity: 20 mg

For one film-coated tablet.

For a full list of excipients, see section 6.1

Active Ingredient Description
Diosmin

Diosmin (diosmetin 7-O-rutinoside), a flavone derivative also known as venosmine, is a glycoside of diosmetin, which in turn is the 4'-methoxy derivative of luteolin. Diosmin prolongs the vasoconstrictor effect of norepinephrine on the vein wall, increasing venous tone, and therefore reducing venous capacitance, distensibility, and venous stasis. This increases the venous return and reduces venous hyperpressure present in patients suffering from CVI.

Hesperidin
List of Excipients

Sodium starch glycolate, microcrystalline cellulose, gelatine, magnesium stearate, talc, titanium.

Film-coating: dioxide (E 171), glycerol, sodium lauryl sulphate, macrogol 6000, hypromellose, yellow iron oxide (E 172), red iron oxide (E 172).

Pack sizes and marketing

15 or 30 tablets in blister packs (PVC-Aluminium).

Not all pack sizes may be marketed.

Marketing authorization holder

Les Laboratoires Servier – France.

Drugs

Drug Countries
DAFLON Austria, Brazil, Cyprus, Ecuador, Spain, France, Hong Kong, Malta, Nigeria, Singapore, Tunisia, Turkey

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