DHC CONTINUS Tablet Ref.[8558] Active ingredients: Dihydrocodeine

Source: Medicines and Medical Devices Safety Authority (NZ)  Revision Year: 2017  Publisher: Distributed on behalf of Mundipharma New Zealand Limited by: Pharmaco (N.Z.) Ltd, 4 Fisher Crescent, Mt Wellington, Auckland 1060, Ph: (09) 377-3336, Toll Free [Medical Enquiries]: 0800 773 310

Therapeutic indications

DHC CONTINUS tablets are recommended for use in the treatment of post-operative pain, and pain associated with cancer.

DHC CONTINUS tablets are also indicated for the treatment of opioid-responsive, chronic severe pain of non-malignant origin, after other conservative methods of analgesia have been tried. It is indicated for use in accordance with the current guidelines on chronic pain management and where there is no psychological contraindication, medicine-seeking behaviour or history of medicine misuse.

Posology and method of administration

Adults and children over 12 years of age

The tablets should be taken at twelve-hourly intervals at a dose of 60-120mg twice daily depending on the severity of the patient’s pain. The maximum recommended dose is 240mg daily since higher doses do not provide any further analgesic effect.

Children 12 years or under

Not recommended.

Elderly and Special Risk Groups

DHC CONTINUS tablets should be administered initially at the lowest dose possible in elderly or debilitated patients, patients with impaired renal function, impaired hepatic function, or hypothyroidism.

Method of administration

DHC CONTINUS tablets must be swallowed whole and not broken, chewed or crushed.

Overdose

Signs and Symptoms

Acute overdosage with dihydrocodeine can be manifested by somnolence progressing to stupor or coma, miotic pupils, bradycardia, hypotension, rhabdomyolysis and respiratory depression or apnoea, which may – in severe cases – result in a fatal outcome.

Treatment

A patent airway must be maintained. The pure opioid antagonists are specific antidotes against symptoms from opioid overdose. Other supportive measures should be employed as needed. For advice on the management of overdose please contact the National Poisons Centre on 0800 POISON (0800 764766).

Shelf life

3 years.

Special precautions for storage

Store below 30°C. Protect from light and moisture. Keep out of reach of children.

Nature and contents of container

60 tablets. Bottles with polypropylene lid and polyethylene body.

Special precautions for disposal and other handling

None.

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