ESTREVA Gel Ref.[50461] Active ingredients: Estradiol

Source: Web Search 

12.1. Mechanism of Action

Hormone – natural Estrogen (Genito-urinary system and sex hormones).

General estrogen therapy by percutenous route allowing: Use of estrogen naturally secreted by the ovary, 17 β estradiol;

Avoiding the effect known as post-hepatic passage responsible for an increase in the synthesis of angiotensinogen, VLDL lipoproteins and certain coagulation factors which are believed to favour cardiovascular, thrombo-embolic and metabolic side effects.

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