GALFER Capsule Ref.[49965] Active ingredients: Ferrous fumarate

Source: Medicines & Healthcare Products Regulatory Agency (GB)  Revision Year: 2019  Publisher: Thornton & Ross Limited, Linthwaite, Huddersfield, West Yorkshire, HD7 5QH, United Kingdom

5.1. Pharmacodynamic properties

Iron is a haematinic essential for satisfactory erythropoiesis during haemoglobin synthesis.

5.2. Pharmacokinetic properties

Absorption of iron is a complicated process. Iron is absorbed throughout the GI tract but it is greatest in the duodenum and proximal jejunum.

Approximately 5-10% of dietary iron is absorbed during prophylaxis and 10-30% in iron deficient subjects. Ferrous ion is easily absorbed compared to ferric ion. Transfer of iron across the placenta is an active process. Excess iron ingested is stored as ferritin and haemosiderin.

5.3. Preclinical safety data

Not applicable.

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