Source: Web Search Revision Year: 2016 Publisher: Pfizer Limited, Ramsgate Road, Sandwich, Kent, CT13 9NJ, UK
GEODON 20 mg/ml powder and solvent for solution for injection.
| Pharmaceutical Form |
|---|
|
Powder and Solvent for solution for injection. White to off-white powder. Clear colourless solvent. |
One vial contains ziprasidone mesilate to deliver 20 mg of ziprasidone. After reconstitution, 1ml of solution for injection contains 20 mg ziprasidone.
Excipient(s) with known effects: Contains less than 1 mmol of sodium (20 mg) per dose, and therefore is essentially sodium free.
For the full list of excipients, see section 6.1.
| Active Ingredient | Description | |
|---|---|---|
| Ziprasidone |
Ziprasidone has been shown to be an antagonist at both serotonin type 2A (5HT2A) and dopamine type 2 (D2) receptors. It is proposed that the therapeutic activity is mediated, in part, through this combination of antagonist activities. Ziprasidone is also a potent antagonist at 5HT2C and 5HT1D receptors, a potent agonist at the 5HT1A receptor and inhibits neuronal reuptake of norepinephrine and serotonin. |
| List of Excipients |
|---|
|
Powder: Sulphobutyl ether beta-cyclodextrin sodium Solvent: Water for Injections |
Type 1 flint glass vials containing powder (ziprasidone mesilate). The vials are sealed with butyl rubber lyophile stoppers and flip-off aluminium seals.
Type 1 flint glass ampoules containing solvent (Water for Injections).
Pack size: 1 vial and 1 ampoule per carton.
Pfizer Limited, Ramsgate Road, Sandwich, Kent, CT13 9NJ, UK
PA019/052/005
Date of first authorization: 08 March 2002
Date of last renewal: 01 August 2010
| Drug | Countries | |
|---|---|---|
| GEODON | Brazil, Cyprus, Ireland, Israel, Mexico, United States, South Africa |
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