GEODON Powder for solution for injection Ref.[51057] Active ingredients: Ziprasidone

Source: Web Search  Revision Year: 2016  Publisher: Pfizer Limited, Ramsgate Road, Sandwich, Kent, CT13 9NJ, UK

Product name and form

GEODON 20 mg/ml powder and solvent for solution for injection.

Pharmaceutical Form

Powder and Solvent for solution for injection.

White to off-white powder.

Clear colourless solvent.

Qualitative and quantitative composition

One vial contains ziprasidone mesilate to deliver 20 mg of ziprasidone. After reconstitution, 1ml of solution for injection contains 20 mg ziprasidone.

Excipient(s) with known effects: Contains less than 1 mmol of sodium (20 mg) per dose, and therefore is essentially sodium free.

For the full list of excipients, see section 6.1.

Active Ingredient Description

Ziprasidone has been shown to be an antagonist at both serotonin type 2A (5HT2A) and dopamine type 2 (D2) receptors. It is proposed that the therapeutic activity is mediated, in part, through this combination of antagonist activities. Ziprasidone is also a potent antagonist at 5HT2C and 5HT1D receptors, a potent agonist at the 5HT1A receptor and inhibits neuronal reuptake of norepinephrine and serotonin.

List of Excipients


Sulphobutyl ether beta-cyclodextrin sodium


Water for Injections

Pack sizes and marketing

Type 1 flint glass vials containing powder (ziprasidone mesilate). The vials are sealed with butyl rubber lyophile stoppers and flip-off aluminium seals.

Type 1 flint glass ampoules containing solvent (Water for Injections).

Pack size: 1 vial and 1 ampoule per carton.

Marketing authorization holder

Pfizer Limited, Ramsgate Road, Sandwich, Kent, CT13 9NJ, UK

Marketing authorization dates and numbers


Date of first authorization: 08 March 2002
Date of last renewal: 01 August 2010


Drug Countries
GEODON Brazil, Cyprus, Ireland, Israel, Mexico, United States, South Africa

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