GONADORELIN Powder for solution for injection Ref.[9559] Active ingredients: Gonadorelin

Source: Medicines & Healthcare Products Regulatory Agency (GB)  Revision Year: 2020  Publisher: Intrapharm Laboratories Limited, The Courtyard Barns, Choke Lane, Cookham Dean, Maidenhead, Berkshire SL6 6PT, United Kingdom

Pharmacodynamic properties

Gonadorelin stimulates the synthesis of follicle stimulating hormone and luteinising hormone in the anterior lobe of the pituitary as well as their release.

Pharmacokinetic properties

Gonadorelin is rapidly hydrolysed in plasma and excreted in urine with a half life of about 4 minutes.

Preclinical safety data

Non-clinical safety data reveal no special hazard for humans based on conventional studies of safety pharmacology, repeated dose toxicity, genotoxicity, carcinogenic potential, toxicity to reproduction and development.

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