HALF BETA-PROGRANE Sustained release capsule Ref.[49926] Active ingredients: Propranolol

Source: Medicines & Healthcare Products Regulatory Agency (GB)  Revision Year: 2020  Publisher: Tillomed Laboratories Ltd, 220 Butterfield, Great Marlings, Luton, LU2 8DL

Product name and form

Half Beta – Prograne 80mg Sustained Release Capsules.

Pharmaceutical Form

Sustained Release Capsule.

Size 3 capsules with opaque white caps and colourless transparent bodies filled with regular creamy white microgranules.

Qualitative and quantitative composition

Each capsule contains 80 mg of propranolol hydrochloride.

Excipients with known effect: The capsule contains Neutral micogrananules (sugar-starch) and Sulfur Dioxide (E220).

For the full list of excipients, see section 6.1.

Active Ingredient Description
Propranolol

Propranolol is a competitive antagonist at both beta, and beta2-adrenoceptor, but has membrane stabilising activity at concentrations exceeding 1-3mg/litre, though such concentrations are rarely achieved during oral therapy. Competitive beta-blockade has been demonstrated in man by a parallel shift to the right in the dose-heart rate response curve to beta-agonists such as isoprenaline.

List of Excipients

Neutral microgranules
Povidone
Ethylcellulose
Talc
Capsule Components
Gelatine
Titanium Dioxide
Sulfur Dioxide (E220)

Pack sizes and marketing

Blister packs:

PVC: Colourless 250 micron thickness

Aluminium: 25 microns thickness

28 capsules per pack, 14 capsules per blister strip.

Not all packs sizes may be marketed.

Marketing authorization holder

Tillomed Laboratories Ltd, 220 Butterfield, Great Marlings, Luton, LU2 8DL

Marketing authorization dates and numbers

PL 11311/0017

25/02/2009

Drugs

Drug Countries
BETA-PROGRANE Ireland, United Kingdom
HALF BETA-PROGRANE Ireland, United Kingdom

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