HYPOVASE Tablet Ref.[8177] Active ingredients: Prazosin

Source: Medicines & Healthcare Products Regulatory Agency (GB)  Revision Year: 2021  Publisher: Pfizer Limited, Ramsgate Road, Sandwich, Kent, CT13 9NJ, United Kingdom

Product name and form

Hypovase 1 mg tablets.

Pharmaceutical Form

Tablet.

White oblong tablets scored on both sides and engraved “M6” on one side.

The tablet can be divided into equal doses.

Qualitative and quantitative composition

Prazosin hydrochloride equivalent to 1 mg prazosin based on a potency of 93.1 % base activity.

For the full list of excipients, see section 6.1.

Active Ingredient Description
Prazosin

Prazosin causes a decrease in total peripheral vascular resistance through selective inhibition of postsynaptic alpha-1-adrenoreceptors in vascular smooth muscle. Prazosin has been found to successfully reduce the severity of the signs, symptoms, frequency and duration of attacks, in patients with Raynaud’s disease.

List of Excipients

Calcium phosphate dibasic anhydrous
Maize starch
Microcrystalline cellulose
Magnesium stearate
Sodium lauryl sulfate

Pack sizes and marketing

PVC/Aluminium blisters in cartons of 60 tablets (blister strips of 4 × 15 tablets).

Marketing authorization holder

Pfizer Limited, Ramsgate Road, Sandwich, Kent, CT13 9NJ, United Kingdom

Marketing authorization dates and numbers

PL 00057/0106R

Date of first authorisation: 19 October 1988
Date of last renewal: 22 November 2004

Drugs

Drug Countries
HYPOVASE Ireland, Malta, United Kingdom

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