INBRIJA Inhalation powder, hard capsule Ref.[116049] Active ingredients: Levodopa

Source: European Medicines Agency (EU)  Revision Year: 2025  Publisher: Merz Therapeutics GmbH, Eckenheimer Landstraße 100, 60318 Frankfurt am Main, Germany

Product name and form

Inbrija 33 mg inhalation powder, hard capsules.

Pharmaceutical Form

Inhalation powder, hard capsule.

White opaque capsules containing white powder, with "A42" printed in black on the cap of the capsule and two black bands printed on the body of the capsule.

Qualitative and quantitative composition

Each hard capsule contains 42 mg levodopa.

Each delivered dose contains 33 mg levodopa.

For the full list of excipients, see section 6.1.

Active Ingredient

Levodopa is a precursor of dopamine, and is given as dopamine replacement therapy in Parkinson's disease.

List of Excipients

Capsule content:

Colfosceril palmitate (DPPC)
Sodium chloride

Capsule shell:

Hypromellose
Titanium dioxide (E171)
Carrageenan
Potassium chloride
Carnauba wax
Maize starch

Ink:

Shellac
Black iron oxide (E172)
Propylene glycol
Potassium hydroxide

Pack sizes and marketing

The hard capsules are supplied in Aluminium/PVC/Aluminium peel-off blisters. Each perforated unit-dose blister strip contains 4 hard capsules.

The Inbrija inhaler is made of polybutylene terephthalate (PBT), polycarbonate (PC) and polypropylene (PP). Puncturing tines and springs are made from stainless steel.

Carton containing 16 hard capsules (4 blister strips) and one inhaler.

Carton containing 32 hard capsules (8 blister strips) and one inhaler.

Carton containing 60 hard capsules (15 blister strips) and one inhaler.

Carton containing 92 hard capsules (23 blister strips) and one inhaler.

Not all pack sizes may be marketed.

Marketing authorization holder

Merz Therapeutics GmbH, Eckenheimer Landstraße 100, 60318 Frankfurt am Main, Germany

Marketing authorization dates and numbers

EU/1/19/1390/001
EU/1/19/1390/002
EU/1/19/1390/003
EU/1/19/1390/004

Date of first authorisation: 19 September 2019
Date of latest renewal: 13 June 2024

Drugs

Drug Countries
INBRIJA Austria, Estonia, France, Croatia, Ireland, Italy, Lithuania, Poland, United States

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