KRISFED Tablet Ref.[115645] Active ingredients: Chlorphenamine

Source: Registered Drug Product Database (NG)  Publisher: Krishat Pharma Industries Limited, KM 15, Lagos-Ibadan Expressway, Ibadan, Oyo State, NIGERIA, Email: info@krishatpharma.com, Company contacts details, operations@krishatpharma.com

5.1. Pharmacodynamic properties

Mechanism of action

Chlorphenamine is a first-generation antihistamine that blocks Hl histamine receptors, reducing allergic symptoms such as itching, swelling, and congestion.

5.2. Pharmacokinetic properties

Absorption

Rapidly absorbed from the gastrointestinal tract; onset of action within 30 minutes.

Distribution

Widely distributed in body tissues, crosses the blood-brain barrier.

Metabolism

Metabolized in the liver.

Excretion

Excreted primarily in urine; half-life is approximately 12-15 hours.

5.3. Preclinical safety data

No relevant preclinical data available beyond those already addressed in other sections of the SmPC.

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