Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2017 Publisher: Aspen Pharma Trading Limited, 3016 Lake Drive, Citywest Business Campus, Dublin 24, Ireland
Pharmacotherapeutic group (ATC code): N01BB01
Bupivacaine is a long acting local anaesthetic agent of the amide type.
Moderate muscular relaxation of lower extremities.
Motor blockade of the abdominal muscles.
Marcain Heavy is hyperbaric and its initial spread in the intrathecal space is affected by gravity.
Rapid onset of action and long duration i.e. T10–T12 segments – duration 2–3 hours.
Muscular relaxation of lower extremities lasts 2–2.5 hours.
Blockade of the abdominal muscles lasts 45–60 minutes. The duration of motor blockade does not exceed duration of analgesia.
In children the pharmacokinetics are similar to that in adults.
Bupivacaine hydrochloride is a well-established active ingredient.
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