MOXIFLOXACIN Solution for infusion Ref.[116545] Active ingredients: Moxifloxacin

Source: Health Products Regulatory Authority (IE)  Revision Year: 2025  Publisher: Fresenius Kabi Deutschland GmbH, Else-Kroener Strasse 1, Bad Homburg v.d.H 61352, Germany

Product name and form

Moxifloxacin 400 mg/250 ml Solution for Infusion, KabiPac bottles.

Pharmaceutical Form

Solution for infusion.

Clear yellow solution.

pH of solution is between 5.0 and 6.0.

Osmolality of solution: 260–330 mOsm.

Qualitative and quantitative composition

Each bottle of 250 ml contains 400 mg moxifloxacin (as hydrochloride).

Each ml contains 1.6 mg moxifloxacin (as hydrochloride).

Excipient with known effect:

250 ml of solution for infusion contains 54.4 mmol sodium.

For the full list of excipients, see section 6.1.

Active Ingredient

Moxifloxacin, a fourth-generation fluoroquinolone, has in vitro activity against a wide range of Gram-positive and Gram-negative pathogens. The bactericidal action of moxifloxacin results from the inhibition of both type II topoisomerases (DNA gyrase and topoisomerase IV) required for bacterial DNA replication, transcription and repair.

List of Excipients

Sodium acetate trihydrate
Sodium sulfate, anhydrous
Sulfuric acid (for pH-adjustment)
Water for injections

Pack sizes and marketing

Moxifloxacin is packed in:

Low-density polyethylene bottles (KabiPac) as primary packaging closed with a cap containing a rubber disc to allow insertion of the needle.

Pack sizes:

Polyethylene bottle (KabiPac): 1, 10, 20, 25 and 40.

Not all pack sizes may be marketed.

Marketing authorization holder

Fresenius Kabi Deutschland GmbH, Else-Kroener Strasse 1, Bad Homburg v.d.H 61352, Germany

Marketing authorization dates and numbers

PA2059/013/001

Date of first authorisation: 17th January 2014
Date of last renewal: 27th November 2018

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