MUCOSOLV Capsule Ref.[50533] Active ingredients: Carbocisteine

Source: Health Products Regulatory Authority (ZA)  Revision Year: 2022  Publisher: Cipla Medpro (Pty) Ltd., Building 9, Parc du Cap, Mispel Street, Bellville, 7530, RSA Customer care: 080 222 6662

5.1. Pharmacodynamic properties

Pharmacological classification: A 10.1 Antitussives and expectorants
ATC code: R05CB03

Carbocisteine reduces the viscosity of non-infected secretions from mucous cells in the respiratory tract.

Carbocisteine is used for its mucolytic activity in respiratory disorders associated with productive cough.

5.2. Pharmacokinetic properties

Carbocisteine is rapidly and well absorbed from the gastrointestinal tract and peak plasma concentrations occur about two (2) hours after an oral dose. It appears to penetrate into lung tissue and respiratory mucus. Carbocisteine is excreted in the urine as unchanged substance and metabolites. Acetylation, decarboxylation, and sulfoxidation have been identified as the major metabolic pathways. Sulfoxidation may be governed by genetic polymorphism.

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