Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2020 Publisher: Alcon Eye Care UK Limited, Park View, Riverside Way, Watchmoor Park, Camberley, Surrey, GU15 3YL, United Kingdom
Ophthalmologicals; Mydriatics and Cycloplegics.
ATC Code: S01FA06
Tropicamide is an anticholinergic which blocks the responses of the sphincter muscle of the iris and the ciliary muscle to cholinergic stimulation thus dilating the pupil (mydriasis). At higher concentrations (1%), tropicamide also paralyses accommodation. This preparation acts rapidly and has a relatively short duration of action.
Tropicamide administered topically to the human eye does not bind to tissues as firmly as does atropine. The wash out time for half recovery of carbachol responsiveness was shown to be less than 15 minutes for non-pigmented iris and 30 minutes for pigmented iris.
There are no preclinical data of relevance to the prescriber which are additional to that already included in other sections of the SPC.
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