PERCUTOL Ointment Ref.[7282] Active ingredients: Glyceryl trinitrate

Source: Medicines & Healthcare Products Regulatory Agency (GB)  Revision Year: 2017  Publisher: Aspire Pharma Limited, Unit 4 Rotherbrook Court, Bedford Road, Petersfield, Hampshire, GU32 3QG, United Kingdom

Therapeutic indications

Prophylaxis of angina pectoris.

Posology and method of administration

Topical application.

Adults (including elderly)

The usual dose is 1 to 2 inches squeezed from the tube, although some patients may require more. This dose may be repeated every 3 to 4 hours as required.

The dose may be titrated to individual patients' needs by finding the dose that causes headache and then reducing this dose by half an inch. Half an inch of ointment should be applied on the first day, one inch on the second, etc. increasing by half an inch per day until headache occurs and then reducing by half an inch. If several applications per day are required the dose may need to be reduced.

The ointment may be conveniently measured and applied using the paper “Applirules” enclosed in the carton. After squeezing the required length of ointment onto the “Applirule” it should be pressed on to any convenient area of skin (e.g. chest, thigh, or arm) until the ointment is spread in a thin layer under the paper. The ointment should not be rubbed in. The “Applirule” may be secured in place with surgical tape.

Children

The safety and efficacy of Percutol in children has not been established.

Overdose

A hypotensive headache is a sign of overdosage. High doses of glyceryl trinitrate may cause marked hypotension and collapse, however topical application reduces the likelihood of overdosage and the effect can be quickly terminated by washing the ointment off the skin.

Shelf life

Shelf life: 36 months.

Special precautions for storage

Store below 25°C.

Nature and contents of container

Collapsible aluminium tube containing 60g.

Special precautions for disposal and other handling

None stated.

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