Source: Health Products Regulatory Authority (IE) Revision Year: 2011 Publisher: Carinopharm GmbH, Bahnhofstraße 18, 31008 Elze, Germany
Enoximone, an imidazolone, has both positive inotropic and vasolidator properties, inhibiting cardiac phosphodiesterase III with an increase in cAMP.
Enoximone half-life ranged from 3 to 8 hours for enoximone and 6-11 hours for the sulphoxide.
0.45% of the intact drug was recovered from the urine and 74% of the metabolite, which is pharmacologically active.
Not applicable.
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