Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2021 Publisher: GlaxoSmithKline Consumer Healthcare (UK) Trading Limited, 980 Great West Road, Brentford, Middlesex, TW8 9GS, UNITED KINGDOM
Piriton tablets are indicated for symptomatic control of all allergic conditions responsive to antihistamines, including hay fever, vasomotor rhinitis, urticaria, angioneurotic oedema, food allergy, drug and serum reactions, insect bites.
Also indicated for the symptomatic relief of itch associated with chickenpox.
Oral Administration only
Do not exceed the stated dose or frequency of dosing
Minimum dosing interval: 4 hours
Do not use continuously for more than two weeks without consulting a doctor.
1 tablet 4 to 6 hourly.
Maximum daily dose: 6 tablets (24 mg) in any 24 hours.
The elderly are more likely to experience neurological anticholinergic effects. Consideration should be given to using a lower daily dose (e.g. a maximum of 12 mg in any 24 hours).
½ tablet 4 to 6 hourly.
Maximum daily dose: 3 tablets (12mg) in any 24 hours.
Not recommended for children under 6 years.
Patients with renal or hepatic impairment should seek doctor’s advice prior to taking this medicine. (See Section 4.4 Special warnings and precautions for use).
The estimated lethal dose of chlorphenamine is 25 to 50mg/kg body weight. Symptoms and signs include sedation, paradoxical excitation of the CNS, toxic psychosis, convulsions, apnoea, anticholinergic effects, dystonic reactions and cardiovascular collapse including arrhythmias.
Management should be as clinically indicated or as recommended by the national poisons centres where available.
Symptomatic and supportive measures should be provided with special attention to cardiac, respiratory, renal and hepatic functions and fluid and electrolyte balance. If overdosage is by the oral route, treatment with activated charcoal should be considered provided there are no contraindications for use and the overdose has been taken recently (treatment is most effective if given within an hour of ingestion). Treat hypotension and arrhythmias vigorously. CNS convulsions may be treated with i.v. diazepam. Haemoperfusion may be used in severe cases.
3 years.
Do not store above 30°C.
The tablets are supplied in securitainers containing 50 or 500 tablets or blister packs containing 30, 45, 60 or 100 tablets.
For detailed instructions for use refer to the Patient Information Leaflet in every pack.
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