Source: Health Products Regulatory Authority (ZA) Revision Year: 2020 Publisher: PHARMACARE LIMITED, Healthcare Park, Woodlands Drive, Woodmead 2191
A 24 Mineral substitutes, electrolytes
The tablets are especially formulated in a slow release form to minimise the possibility of gastrointestinal irritation which may arise from a localised high concentration of potassium in the gut. Potassium is of fundamental importance in the ionic exchange of cellular metabolism. Potassium is the predominating cation of intracellular fluid and erythrocytes.
Following a single dose of oral potassium, potassium chloride is released over a period of approximately 4 hours. Renal excretion of potassium chloride following ingestion occurs 30 to 60 minutes later than when the same dose is given in the form of a solution.
In the presence of a normal potassium balance and normal renal function, approximately 90% of the potassium supplied by oral potassium is excreted renally within 7 hours, and more than 98% within 24 hours.
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