PRESESE Film-coated tablet Ref.[115297] Active ingredients: Bisoprolol

Source: Health Products Regulatory Authority (ZA)  Revision Year: 2024  Publisher: Aurogen South Africa (Pty) Ltd, Woodhill Office Park, Building 1, First floor, 53 Phillip Engelbrecht Avenue, Meyersdal, Ext. 12, 1448, Johannesburg, South Africa

Product name and form

PRESESE 5 mg TABLETS (tablet).

PRESESE 10 mg TABLETS (tablet).

Pharmaceutical Form

PRESESE 5 mg TABLETS: Yellow coloured, circular, biconvex, film-coated tablets, debossed with 'I and break line' on one side and '11' on the other side.

PRESESE 10 mg TABLETS: Yellow coloured, circular, biconvex, film-coated tablets, debossed with 'I and break line' on one side and '13' on the other side.

Qualitative and quantitative composition

PRESESE 5 mg TABLETS: Each film-coated tablet contains bisoprolol fumarate (2:1) 5 mg. Sugar free.

PRESESE 10 mg TABLETS: Each film-coated tablet contains bisoprolol fumarate (2:1) 10 mg. Sugar free.

For full list of excipients, see section 6.1.

Active Ingredient

Bisoprolol is a potent highly beta1-selective-adrenoceptor blocking agent, lacking intrinsic stimulating and without relevant membrane stabilising activity.

List of Excipients

Calcium hydrogen phosphate
Cellulose microcrystalline
Crospovidone
Magnesium stearate
Silica colloidal anhydrous

The coating material of PRESESE contains:

Hypromellose
Macrogol/peg 400
Titanium dioxide (c.i. no: 77891)
Purified water
Iron oxide yellow

Pack sizes and marketing

PRESESE 5 mg TABLETS AND PRESESE 10 mg TABLETS

Blister pack:

Tablets are packed in printed peelable lidding silver foil (50 g/m² paper/12 micron polyster/20 micron Aluminium foil/7 g/m² HSL) and cold form film (25 micron polyamide/45 micron Aluminium foil/60 micron PVC film). One blister contains 10 tablets.

Pack size: 30's: Each carton contains 3 blisters of 10 tablets each.

HDPE Container Pack:

Tablets are packed in white opaque round 40 ml HDPE container with a white opaque ribbed stock (RS) HDPE closure, with induction sealing wad containing one silica gel sachet. Each container which is enclosed in an outer cardboard carton contains 30 tablets.

Pack size: 30's - One HDPE container contains 30 tablets.

Marketing authorization holder

Aurogen South Africa (Pty) Ltd, Woodhill Office Park, Building 1, First floor, 53 Phillip Engelbrecht Avenue, Meyersdal, Ext. 12, 1448, Johannesburg, South Africa

Marketing authorization dates and numbers

PRESESE 5 mg TABLETS: 45/5.2/0866
PRESESE 10 mg TABLETS: 45/5.2/0867

11 June 2018

Drugs

Drug Countries
PRESESE South Africa

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