PROCARDIN Film-coated tablet Ref.[28220] Active ingredients: Dipyridamole

Source: Υπουργείο Υγείας (CY)  Revision Year: 2015  Publisher: MEDOCHEMIE LTD, 1-10 Constantinoupoleos street, 3011 Limassol, Cyprus

4.1. Therapeutic indications

Procardin is indicated as an adjunct to oral anticoagulation for prophylaxis of thromboembolism associated with prosthetic heart valves.

4.2. Posology and method of administration

Posology

Adults

300–600mg daily in three or four doses.

Paediatric population

Procardin in not recommended for children.

Method of administration

Procardin should usually be taken before meals.

4.9. Overdose

Symptom

Due to the low number of observations, experience with dipyridamole overdosage is limited.Symptoms such as a warm feeling, flushes, sweating, restlessness, feeling of weakness, dizziness and anginal complaints can be expected. A drop in blood pressure and tachycardia might be observed.

Management

Symptomatic therapy is recommended. Administration of xanthine derivatives (e.g. aminophylline) may reverse the haemodynamic effects of dipyridamole overdose. Due to its wide distribution to tissues and its predominantly hepatic elimination, dipyridamole is not likely to be accessible to enhanced removal procedures.

6.3. Shelf life

60 months.

6.4. Special precautions for storage

Store below 30°C in the original package, in order to protect from light.

6.5. Nature and contents of container

Packs of 20, 50, 100, and 120 are available, in PVC/Alu blisters. Packs of 500 and 1000 tablets are available in securitainers.

Not all pack sizes may be marketed.

6.6. Special precautions for disposal and other handling

No special requirements for disposal.

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