PROLENSA Ophthalmic solution Ref.[10907] Active ingredients: Bromfenac

Source: FDA, National Drug Code (US)  Revision Year: 2020 

Product description

PROLENSA (bromfenac ophthalmic solution) 0.07% is a sterile, topical, nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Each mL of PROLENSA contains 0.805 mg bromfenac sodium sesquihydrate (equivalent to 0.7 mg bromfenac free acid). The USAN name for bromfenac sodium sesquihydrate is bromfenac sodium. Bromfenac sodium is designated chemically as sodium [2-amino-3-(4-bromobenzoyl) phenyl] acetate sesquihydrate, with an empirical formula of C15H11BrNNaO3•1½H2O.

The chemical structure for bromfenac sodium sesquihydrate is:

Bromfenac sodium is a yellow to orange crystalline powder. The molecular weight of bromfenac sodium is 383.17.

PROLENSA ophthalmic solution is supplied as a sterile aqueous 0.07% solution, with a pH of 7.8. The osmolality of PROLENSA ophthalmic solution is approximately 300 mOsmol/kg.

<Each mL of PROLENSA ophthalmic solution contains:

Active: Each mL contains bromfenac sodium sesquihydrate 0.0805%, which is equivalent to bromfenac free acid 0.07%.

Preservative: benzalkonium chloride 0.005%

Inactives: boric acid, edetate disodium, povidone, sodium borate, sodium sulfite, tyloxapol, sodium hydroxide to adjust pH, and water for injection, USP.

Dosage Forms and Strengths

Topical ophthalmic solution: bromfenac 0.07%.

How Supplied

PROLENSA (bromfenac ophthalmic solution) 0.07% is supplied in a white LDPE plastic squeeze bottle with a 15 mm LDPE white dropper tip and 15 mm polypropylene gray cap as follows:

  • 3 mL in a 7.5 mL container (NDC 24208-602-03)

Distributed by: Bausch + Lomb, a division of Bausch Health US, LLC, Bridgewater, NJ 08807 USA

Under License From: Senju Pharmaceutical Co., Ltd., Osaka, Japan 541-0046

Drugs

Drug Countries
PROLENSA Canada, United States

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