PROVOCHOLINE Powder for solution Ref.[10340] Active ingredients: Methacholine

Source: FDA, National Drug Code (US)  Revision Year: 2020 

Product description

Methacholine chloride, the active ingredient of Provocholine, is a parasympathomimetic (cholinergic) bronchoconstrictor agent. Provocholine (methacholine chloride) powder for solution is administered by oral inhalation.

Chemically, methacholine chloride (the active ingredient) is 1-propanaminium, 2-(acetyloxy)-N,N,N,trimethyl, chloride. It is a white to practically white deliquescent compound, soluble in water, alcohol and chloroform and insoluble in ether. Aqueous solutions are neutral to litmus.

Methacholine chloride has an empirical formula of C8H18ClNO2, a molecular weight of 195.69, and the following structural formula:

Each vial of Provocholine contains 100 mg of methacholine chloride powder.

Dosage Forms and Strengths

Powder for Solution: 100 mg of white to off-white crystalline powder in amber glass vials (powder is reconstituted and then diluted prior to administration).

How Supplied

Provocholine (methacholine chloride) powder for solution: in amber glass vials that contain 100 mg of methacholine chloride powder, white to off-white in color. Cartons have 6 vials (NDC 64281-100-06).

Provocholine powder for solution pharmacy bulk package (not for direct use): in a plastic drum containing 1,000 g of methacholine chloride powder in a foil package (NDC 64281-100-07).

Distributed by: Methapharm, Inc. Coral Springs, FL 33065.

Drugs

Drug Countries
PROVOCHOLINE Canada, Spain, Israel, Japan, United States

© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.