PYRALVEX Oromucosal solution Ref.[115951] Active ingredients: Anthraquinone glycosides Salicylic acid

Source: Health Products Regulatory Authority (IE)  Revision Year: 2007  Publisher: Norgine Limited, Chaplin House, Widewater Place, Moorhall Road, Harefield, Uxbridge, Middlesex, UB9 6NS, Untied Kingdom

5.1. Pharmacodynamic properties

Pharmacological studies have shown that the active ingredients of PYRALVEX display anti-inflammatory, analgesic and anti-microbial properties, which are the basis of its clinical efficacy.

5.2. Pharmacokinetic properties

Systemic availability of PYRALVEX is unlikely to be significant, owing to the low levels of ingredients administered.

5.3. Preclinical safety data

Preclinical studies indicate that at clinically effective doses, the ingredients in PYRALVEX are unlikely to have any potential for toxic effects.

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