Publisher: Sanofi-aventis Israel ltd, P.O.B. 8090 Netanya 4250499
Respiratory tract infections, infections caused by clamydia, cryptosporidiosis pregnancy toxoplasmosis.
Routine dose:
Adults: 6 to 9 million IU/24 hours, i.e. 4 to 6 tablets per day in 2 to 3 intakes.
Children: 1.5 to 3 million IU per 10 kg of body weight per day in 2 to 3 intakes.
Sore throats should be treated for 10 days.
Adults: 3 million IU/12 hours.
Children: 75,000 IU/kg/12 hours.
For 5 days.
No dose adjustment is necessary.
Tablets should be swallowed whole with a glass of water
There is no known toxic dose for spiramycin.
Expected signs of overdose are gastrointestinal: nausea, vomiting, diarrhea.
Due to the risk of QT prolongation, ECG monitoring is advised.
In the event of overdose, the QT interval should be determined, especially where other risk factors are present (hypokalemia, congenital lengthening of QT interval, other medicinal products lengthening QT interval and/or inducing torsades de pointes).
There is no specific antidote.
Symptomatic treatment is recommended.
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