SYRENEV PLUS Capsule Ref.[115622] Active ingredients: Pregabalin Vitamin B12

Source: Registered Drug Product Database (NG)  Publisher: SUNRISE REMEDIES PVT. LTD., At: Block No. 2244, At & Post-Santej, Tal-Kalol. Dist-Gandhinagar

4.1. Therapeutic indications

Pregabalin/Methylcobalamin are used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:

  • Nerve damage pain
  • Pain in neurological disorders
  • Nerve damage
  • Seizures
  • Anxiety disorder in adults
  • Anemia
  • Numbness and tingling

4.2. Posology and method of administration

The dose range is 150 to 600 mg per day given in either two or three divided doses along with methylcobalamin 1.5 mcg to 6.0 mg. Pregabalin treatments can be started at a dose of 150 mg per day given as two or three divided doses & methylcobalamin 1.5 mg per day. The dose may be increased to 300 mg per days after an interval of 3 of 7 days, and if needed, to a maximum dose of 600 mg per day.

4.9. Overdose

In overdoses up to 15 g, no unexpected adverse reactions were reported.

In the post-marketing experience, the most commonly reported adverse reactions observed when pregabalin was taken in overdose included somnolence, confusional state, agitation, and restlessness.

Treatment of pregabalin overdose should include general supportive measures and may include haemodialysis if necessary.

6.3. Shelf life

24 months from the date of manufacturing.

6.4. Special precautions for storage

Store in a dry place below 30°C, protected from light & moisture.

6.5. Nature and contents of container

3 × 10 Capsules Alu-Alu Blisters packed in printed carton along with package insert.

6.6. Special precautions for disposal and other handling

No special requirements.

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