VOLPLEX Solution for infusion Ref.[9421] Active ingredients: Gelatin

Source: Medicines & Healthcare Products Regulatory Agency (GB)  Revision Year: 2020  Publisher: Beacon Pharmaceutical Limited, The Bower 4 Roundwood Avenue, Stockley Park, Heathrow, United Kingdom, UB11 1AF

Pharmacodynamic properties

Pharmacotherapeutic group: Gelatin agents
ATC code: B05AA06

Volplex is a colloidal plasma substitute. When used in the treatment of hypovolaemia Volplex produces significant increases in blood volume, cardiac output, stroke volume, blood pressure, urinary output and oxygen delivery.

Volplex promotes osmotic diuresis, thereby helping to protect the kidneys from the adverse effects of hypovolaemia.

Pharmacokinetic properties

The half-life of Volplex is about 4 hours, with the majority of the dose administered being eliminated by renal excretion within 24 hours.

Preclinical safety data

There are no preclinical data of relevance to the prescriber, which are additional to those already included in other sections of the SmPC.

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