Source: FDA, National Drug Code (US) Revision Year: 2026
Narsoplimab-wuug, a mannan-binding lectin-associated serine protease 2 (MASP-2) inhibitor, is a recombinant human immunoglobulin G4 (IgG4) monoclonal antibody produced in Chinese Hamster Ovary cells. The approximate molecular weight is 143 kDa.
YARTEMLEA (narsoplimab-wuug) injection is a sterile, preservative-free, clear to slightly opalescent, slightly yellow to yellow-brown solution for intravenous infusion. Each 2-mL singledose glass vial contains 370 mg of narsoplimab-wuug, arginine hydrochloride (84.3 mg), citric acid monohydrate (1.42 mg), polysorbate 80 (0.2 mg), sodium citrate (8.6 mg), and Water for Injection, USP. Sodium hydroxide and hydrochloric acid were added to adjust the pH to 5.8.
| Dosage Forms and Strengths |
|---|
|
Injection: 370 mg/2 mL (185 mg/mL) as a clear to slightly opalescent, slightly yellow to yellowbrown solution in a single-dose vial. |
| How Supplied |
|---|
|
YARTEMLEA (narsoplimab-wuug) injection is a sterile, preservative-free, clear to slightly opalescent, slightly yellow to yellow-brown solution supplied as one 370 mg/2 mL (185 mg/mL) single-dose vial in a carton (NDC 62225-300-00). Manufactured by: Omeros Corporation, 201 Elliott Avenue West, Seattle, WA 98119 |
| Drug | Countries | |
|---|---|---|
| YARTEMLEA | United States |
© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.