AKURIT

This brand name is authorized in Nigeria. It is also authorized in South Africa.

Active ingredients

The drug AKURIT contains a combination of these active pharmaceutical ingredients (APIs):

1	Isoniazid UNII V83O1VOZ8L - ISONIAZID
	Isoniazid is used mainly in the treatment of pulmonary tuberculosis but it appears to be effective also in the treatment of extrapulmonary lesions, including meningitis and genito-urinary disease.
	Read more about Isoniazid
2	Rifampicin UNII VJT6J7R4TR - RIFAMPIN
	Rifampicin is an active bactericidial antituberculosis drug which is particularly active against the rapidly growing extracellular organisms and also has bactericidial activity intracellularly. Rifampicin inhibits DNA-dependent RNA polymerase activity in susceptible cells. Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme.
	Read more about Rifampicin

Packages

This drug has been approved in Nigeria as follows:

Identifier	Form	Presentation	Description	Approval
04-9278	Film coated tablet	AKURIT TABLETS TAB_FILM_COATED 150 mg; 75 mg 15 X 6	15 RNW-PP-145268 AKURIT TABLETS RIFAMPIN 150 AND ISONIAZID 75 Each film coated tablet contains: Rifampin USP……………………150mg Isoniazid USP 75mg Excipients a Rifampin USP Isoniazid USP Microcrystalline Cellulose USNF Pregelatinized starch (Starch 1500) USNF Crospovidone NF/EP Ascorbic acid USP Colloidal Silicon Dioxide (Aer200) NF/EP Magnesium Stearate NF/EP Hypromellose (Methocel E5 LVP) USP/EP Hypromellose (Methocel E15 LVP) USP/EP Polyethylene glycol 4000 USNF Talc USP Titanium dioxide USP Colour Iron oxide Red LD Si Apr-78 Drugs Imported Products 15X6 Prescription Only Medicine (POM) 4/12/2022 ONIFAM LABORATORIES LIMITED, IDIMU ROAD, ORELOPE EGBEDA, LAGOS. EGBEDA LAGOS 17763208 onifamconsultant@yahoo.com LUPIN LTD, A-28/1, M.I.D.C CHIKALTHANA, AURANGABAD 431210 MAHARASHTRA STATE, INDIA., India	31/10/2023

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group		Classification
J04AM02	Rifampicin and isoniazid	J Antiinfectives for systemic use → J04 Antimycobacterials → J04A Drugs for treatment of tuberculosis → J04AM Combinations of drugs for treatment of tuberculosis
Discover more medicines within J04AM02

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
NG	Registered Drug Product Database	04-9278
ZA	Health Products Regulatory Authority	54/20.2.3/0648