Rifampicin

Chemical formula: C₄₃H₅₈N₄O₁₂ Molecular mass: 822.94 g/mol PubChem compound: 5381226

Active ingredient description

Rifampicin is an active bactericidial antituberculosis drug which is particularly active against the rapidly growing extracellular organisms and also has bactericidial activity intracellularly. Rifampicin inhibits DNA-dependent RNA polymerase activity in susceptible cells. Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code	Group title	Classification
J04AB02	Rifampicin	J Antiinfectives for systemic use → J04 Antimycobacterials → J04A Drugs for treatment of tuberculosis → J04AB Antibiotics
Discover more medicines within J04AB02

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title	Information Source	Document Type
RIFADIN Solvent	Medicines & Healthcare Products Regulatory Agency (GB)	MPI, EU: SmPC
RIFADIN Capsule	Medicines & Healthcare Products Regulatory Agency (GB)	MPI, EU: SmPC

Medicines

Rifampicin is an active ingredient of these brands:

United States (US)

RIFADIN

Australia (AU)

Austria (AT)

Cyprus (CY)

Ecuador (EC)

RIFADEX

Estonia (EE)

BENEMICIN
EREMFAT
RIFADIN
RIFASYNT
RIFCAP
RIMACTAN
SINERDOL
(combination) ISO-EREMFAT
(combination) RIFAMAZID
(combination) RIMACTAZID
(combination) SINERDOL ISO

Finland (FI)

RIMAPEN

France (FR)

RIFADINE
RIMACTAN
(combination) RIFATER
(combination) RIFINAH

Hong Kong (HK)

Ireland (IE)

RIFADIN
(combination) RIFATER
(combination) RIFINAH

Japan (JP)

RIFADIN

Lithuania (LT)

BENEMICIN
RIFOLDIN
(combination) MACOX ZH
(combination) RIFAMAZID

Malta (MT)

EREMFAT
RIFADIN
RIFASYNT
RIMACTANE
(combination) RIFAMAZID
(combination) RIFINAH

Mexico (MX)

RIFADIN
(combination) DOTBAL
(combination) RIFATER

Netherlands (NL)

RIFADIN
(combination) RIFINAH

New Zealand (NZ)

RIFADIN
(combination) RIFINAH

Nigeria (NG)

(combination) AKT-4

Poland (PL)

(combination) RIFAMAZID

Romania (RO)

SINERDOL
(combination) SINERDOL ISO

Singapore (SG)

RIFAREN

South Africa (ZA)

RIFADIN
RIMACTANE
(combination) AFARIS
(combination) AKURIT KID
(combination) CO-AFARIS
(combination) CO-ORIZIT
(combination) CO-RIPYSO
(combination) DUOPIC
(combination) KOXIRIP
(combination) MONTONEX
(combination) MYRIN
(combination) MYRIN PLUS
(combination) MYRIN-P FORTE
(combination) ORIZIT
(combination) RIFAFOUR e-275
(combination) RIFINAH
(combination) RIFIZID
(combination) RIMACTAZID
(combination) RIMTIB
(combination) RIPYSO
(combination) RISOPET
(combination) RITIB

Spain (ES)

RIFALDIN
RIMACTAN
(combination) RIFATER
(combination) RIFINAH
(combination) RIMSTAR

Tunisia (TN)

SINERDOL

Turkey (TR)

United Kingdom (UK)

RIFADIN
RIMACTANE
(combination) RIFATER
(combination) RIFINAH
(combination) VORACTIV

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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