VOLINI

This brand name is authorized in Nigeria.

Active ingredients

The drug VOLINI contains a combination of these active pharmaceutical ingredients (APIs):

`1`	Diclofenac UNII `6TGQ35Z71K` - DICLOFENAC DIETHYLAMINE
	Diclofenac is a non-steroidal anti-inflammatory drug. The mechanism of action of diclofenac in AK may be related to the inhibition of the cycloxygenase pathway leading to reduced prostaglandin E₂ (PGE₂) synthesis. In addition, immunohistochemistry (IHC) from skin biopsies ac revealed that the clinical effects of diclofenac in AK are primarily due to anti-inflammatory, anti-angiogenic and possibly anti-proliferative effects and apoptosis-inducing mechanisms.
	Read more about Diclofenac
`2`	Linseed oil UNII `84XB4DV00W` - LINSEED OIL
`3`	Methyl salicylate UNII `LAV5U5022Y` - METHYL SALICYLATE
	Methyl salicylate has the action of salicylates, causing dilation of the skin vessels. Methyl salicylate is used to prevent bed sores and for hardening the skin of the feet.
	Read more about Methyl salicylate
`4`	Menthol UNII `YS08XHA860` - RACEMENTHOL
	Read more about Menthol

Packages

This drug has been approved in Nigeria as follows:

Identifier	Form	Presentation	Description	Approval
A4-3978	Gel	Volini Gel GEL 1%; 32%;10%; 5%	45 Diclofenac, Linseed Oil, Methylsacylate And Racementhol Gel A4-3978 Volini Gel Diclofenac Diethylamine BP Eq. To Diclofenac Sodium Methyl Salicylate BP W/W; Racementhol BP, W/W; Linseed Oil BP W/W; Preservative: Benzyl Alcohol BP W/W; Gel Base Q.S.; Carbomer Usnf; Polyoxyl Hydrogenated Castor Oil Usnf; Propylene Glycol BP; Butyllated Hydroxyl Toluene BP; Citric Acid Monohydrate BP; Isopropyl Alcohol BP; Disodium Edetate BP; Diethylamine Ih; Purified Water Dermatological Agents Cutaneous/Topical Route BP 1.16% W/W Eq. 1.0%; 10.0% W/W; BP, 5.0% W/W; BP 3.0% W/W; 1.00% W/W; 934 Usnf; 40, BP; Gel Over The Counter (Otc) Ranbaxy Nigeria Limited Sun Pharmaceutical Ind. Limited India 2021-03-01 2026-02-28	01/03/2021

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
NG	Registered Drug Product Database	A4-3978

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