Abaloparatide

PubChem compound: 145705876

Active ingredient description

Abaloparatide is a 34 amino acid peptide that shares 41% homology to parathyroid hormone [PTH] and 76% homology to parathyroid hormone related peptide [PTHrP(1-34)], and is an activator of the PTH1 receptor signalling pathway. Abaloparatide stimulates new bone formation on trabecular and cortical bone surfaces by stimulation of osteoblastic activity. Abaloparatide causes transient and limited increases in bone resorption and increases bone density.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
H05AA04 H Systemic hormonal preparations, excl. Sex hormones and insulins → H05 Calcium homeostasis → H05A Parathyroid hormones and analogues → H05AA Parathyroid hormones and analogues
Discover more medicines within H05AA04

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
ELADYNOS Solution for injection European Medicines Agency (EU) MPI, EU: SmPC
TYMLOS Solution for injection FDA, National Drug Code (US) MPI, US: SPL/PLR

External identifiers

CAS Substance: 247062-33-5
DrugBank Drug: DB05084
PubChem Compound: 145705876
RxNorm Ingredient: 1921069
SNOMED-CT Concept: 735229000
Abaloparatide (substance)
UNII Identifier: AVK0I6HY2U
ABALOPARATIDE

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