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Abatacept

Description

Abatacept is a fusion protein that consists of the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) linked to a modified Fc portion of human immunoglobulin G1 (IgG1). Abatacept selectively modulates a key costimulatory signal required for full activation of T lymphocytes expressing CD28.

ATC Classification

Code
Title
Category
L04AA24
Abatacept
L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AA Selective immunosuppressants

Trade names

Trade name
Countries

Australia Austria Canada Cyprus France

Product Monographs

Monograph
Type
Country
ORENCIA Solution for injection
MPI, EU: SmPC
ORENCIA Powder for concentrate for solution for infusion
MPI, EU: SmPC