Chemical formula: C₁₄H₂₁N₅O₂S Molecular mass: 323.42 g/mol PubChem compound: 78323835
Abrocitinib is a Janus kinase (JAK)1 inhibitor. JAKs are intracellular enzymes which transmit signals arising from cytokine or growth factor-receptor interactions on the cellular membrane to influence cellular processes of haematopoiesis and immune cell function. It is used for the treatment of moderate-to-severe atopic dermatitis in adults.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| D11AH08 | D Dermatologicals → D11 Other dermatological preparations → D11A Other dermatological preparations → D11AH Agents for dermatitis, excluding corticosteroids | |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| CIBINQO Film-coated tablet | European Medicines Agency (EU) | MPI, EU: SmPC |
Abrocitinib is an active ingredient of these brands:
Croatia (HR)Estonia (EE)Finland (FI)Ireland (IE)Israel (IL)Japan (JP)Poland (PL)Romania (RO)Turkey (TR)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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