Aceclofenac

Chemical formula: C₁₆H₁₃Cl₂NO₄  Molecular mass: 354.18 g/mol  PubChem compound: 71771

Therapeutic indications

Aceclofenac is indicated for:

Relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis

Population group: only adults (18 years old or older)

Pain and additionally at least one of
Osteoarthritis
Rheumatoid arthritis
Ankylosing spondylitis

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Aceclofenac is contraindicated in the following cases:

Active bleeding or bleeding diathesis

Bleeding

Pregnancy, third trimester

Pregnancy

Peptic ulcer/haemorrhage

at least one of
Peptic ulcer
Gastrointestinal hemorrhage

History of gastrointestinal bleeding or perforation related to previous NSAIDs therapy

at least one of
Gastrointestinal hemorrhage
Gastrointestinal perforation

Severe renal failure

at least one of

Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

Severe heart failure

at least one of
Heart failure New York Heart Assosiation Class II
Heart failure New York Heart Assosiation Class IΙΙ
Heart failure New York Heart Assosiation Class IV
Ischemic heart disease
Peripheral arterial vascular disease
Cerebrovascular disease

Severe hepatic failure

Hepatic failure stage IV

Known hypersensitivity to non-steroidal anti-inflammatory drugs

Non-steroidal anti-inflammatory drug allergy

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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Summary of Product Characteristics (SPC) 2023: ACECLOFENAC Film-coated tablet
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