Acoltremon

Chemical formula: C₁₈H₂₇NO₂  Molecular mass: 289.204 g/mol  PubChem compound: 11266244

Active ingredient description

Studies in animals suggest that acoltremonis an agonist of transient receptor potential melastatin 8 (TRPM8) thermoreceptors. TRPM8 thermoreceptor stimulation has been shown to activate trigeminal nerve signaling leading to increased basal tear production. The exact mechanism of action for acoltremon in dry eye disease is unknown.

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Document Type Information Source  
 TRYPTYR Ophthalmic solution MPI, US: SPL/PLR FDA, National Drug Code (US)

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

DrugBank Drug: DB19202
PubChem Compound: 11266244
UNII Identifier: 1L7BVT4Z4Z
ACOLTREMON

Medicines

Acoltremon is an active ingredient of these brands:

United States (US)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

 
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