Acrivastine

Active ingredient description

Acrivastine, a structural analog of triprolidine hydrochloride, exhibits H1-antihistaminic activity in isolated tissues, animals, and humans, and has sedative effects in humans. The propionic acid derivative of acrivastine is a metabolite in several animal species (as well as in man) and also exhibits H1-antihistaminic activity.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
R06AX18
Acrivastine
R Respiratory system → R06 Antihistamines for systemic use → R06A Antihistamines for systemic use → R06AX Other antihistamines for systemic use
Discover more medicines within R06AX18

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
SEMPREX D Capsule
Structured Product Labeling (SPL)
US

Medicines

Acrivastine is the active ingredient of these drugs:

Drug
Countries
BENADRYL ALLERGY RELIEF

United Kingdom

SEMPREX

Netherlands

Acrivastine is also found within below combination drugs:

ACRISEU , BENADRYL ALLERGY RELIEF PLUS DECONGESTANT , DUACT , SEMPREX D

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₂₂H₂₄N₂O₂
Molecular mass: 348.438 g/mol

External identifiers

CAS Substance: 87848-99-5
DrugBank Drug: DB09488
KEGG Drug: D02760
PubChem Compound: 5284514
RxNorm Ingredient: 19959
SNOMED-CT Concept: 391716003
Acrivastine (substance)
UNII Identifier: A20F9XAI7W
ACRIVASTINE
 
Next: Usage >