Ademetionine

Active ingredient description

Ademetionine is a naturally occurring amino acid present in virtually all body tissues and fluids. Ademetionine functions primarily as a co-enzyme and donor transfer of the methyl group (transmethylation) is an essential metabolic process in humans and animals. Ademetionine is also a precursor in the formation of physiological sulfurated compounds (cysteine, taurine, glutathione, CoA, etc.) via transsulfuration. It is used for the treatment of intrahepatic cholestasis.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
A16AA02
Ademetionine
A Alimentary tract and metabolism → A16 Other alimentary tract and metabolism products → A16A Other alimentary tract and metabolism products → A16AA Amino acids and derivatives
Discover more medicines within A16AA02

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
TRANSMETIL Tablet / Powder for solution for injection
Summary of Product Characteristics (SPC)

Medicines

Ademetionine is the active ingredient of these drugs:

Drug
Countries
DONAMET

Estonia

GEPSAM

Lithuania

HEPTRAL

Ecuador Estonia

TRANSMETIL

Estonia

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₁₅H₂₂N₆O₅S
Molecular mass: 398.44 g/mol

External identifiers

CAS Substance: 17176-17-9
CAS Substance: 29908-03-0
DrugBank Drug: DB00118
PubChem Compound: 34755
RxNorm Ingredient: 9504
SNOMED-CT Concept: 441816007
Ademetionine (substance)
UNII Identifier: 7LP2MPO46S
ADEMETIONINE
 
Next: Usage >