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Afatinib

Brand names: GILOTRIF GIOTRIF

Description

Afatinib is a potent and selective, irreversible ErbB Family Blocker. Afatinib covalently binds to and irreversibly blocks signalling from all homo- and heterodimers formed by the ErbB family members EGFR (ErbB1), HER2 (ErbB2), ErbB3 and ErbB4.

ATC Classification

Code
Title
Category
L01EB03
Afatinib
L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01E Protein kinase inhibitors → L01EB Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors

Related medicines

MPI, EU: SmPC 2020: GIOTRIF Film-coated tablets

2D Molecule Structure

Unique Ingredient Identifier (UNII)

41UD74L59M - AFATINIB

CAS Registry Number

439081-18-2 - afatinib

 
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