Agalsidase alfa

Description

Agalsidase alfa catalyses the hydrolysis of Gb3, cleaving a terminal galactose residue from the molecule. Treatment with the enzyme has been shown to reduce accumulation of Gb3 in many cell types including endothelial and parenchymal cells. Agalsidase alfa has been produced in a human cell line to provide for a human glycosylation profile that can influence uptake by mannose-6-phosphate receptors on the surface of target cells.

Medicine classification

ATC Code
Title
Class
Agalsidase alfa
A Alimentary tract and metabolism → A16 Other alimentary tract and metabolism products → A16A Other alimentary tract and metabolism products → A16AB Enzymes

Medicines

Drug
Countries

Austria Canada France Hong Kong Lithuania

Product monographs

Monograph
Type
Country

3D Molecule Structure

3D representation of molecule

Unique Ingredient Identifier (UNII)

2HLC17MX9G - AGALSIDASE ALFA

CAS Registry Number

104138-64-9 - agalsidase beta

SNOMED-CT

424905009 - Agalsidase alfa (substance)