Chemical formula: C₁₅H₁₇NO₂ Molecular mass: 243.301 g/mol PubChem compound: 82148
Agomelatine is a melatonergic agonist (MT1 and MT2 receptors) and 5-HT2C antagonist. In humans, agomelatine has positive phase shifting properties; it induces a phase advance of sleep, body temperature decline and melatonin onset.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| N06AX22 | Agomelatine | N Nervous system → N06 Psychoanaleptics → N06A Antidepressants → N06AX Other antidepressants |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| VALDOXAN Film-coated tablets | European Medicines Agency (EU) | MPI, EU: SmPC |
Agomelatine is an active ingredient of these brands:
Austria (AT)
Brazil (BR)Cyprus (CY)Ecuador (EC)Finland (FI)France (FR)Hong Kong (HK)Malta (MT)
Netherlands (NL)Poland (PL)Romania (RO)Singapore (SG)Turkey (TR)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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