Agomelatine

Active ingredient description

Agomelatine is a melatonergic agonist (MT1 and MT2 receptors) and 5-HT2C antagonist. In humans, agomelatine has positive phase shifting properties; it induces a phase advance of sleep, body temperature decline and melatonin onset.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
N06AX22
Agomelatine
N Nervous system → N06 Psychoanaleptics → N06A Antidepressants → N06AX Other antidepressants
Discover more medicines within N06AX22

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
VALDOXAN Film-coated tablets
Summary of Product Characteristics (SPC)

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₁₅H₁₇NO₂
Molecular mass: 243.301 g/mol

External identifiers

CAS Substance: 138112-76-2
DrugBank Drug: DB06594
KEGG Drug: D02578
PubChem Compound: 82148
SNOMED-CT Concept: 698012009
Agomelatine (substance)
UNII Identifier: 137R1N49AD
AGOMELATINE

Medicines

Agomelatine is an active ingredient of these brands:

Austria (AT)

Brazil (BR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Germany (DE)

Hong Kong (HK)

Ireland (IE)

Lithuania (LT)

Malta (MT)

Netherlands (NL)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Turkey (TR)

United Kingdom (UK)

While we strive to include the brand names of medicines across all countries, our index remains incomplete. Therefore, it is possible that this medicine may also be marketed under different names in other countries.

 
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