Aldesleukin, a lymphokine, is produced by recombinant DNA technology and acts as a regulator of the immune response. The biological activities of aldesleukin and native human IL-2, a naturally occurring lymphokine, are comparable. The administration of aldesleukin in murine tumour models has been shown to reduce both tumour growth and spread. The exact mechanism by which aldesleukin-mediated immunostimulation leads to antitumour activity is not yet known.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
|L Antineoplastic and immunomodulating agents → L03 Immunostimulants → L03A Immunostimulants → L03AC Interleukins
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
|PROLEUKIN Powder for solution for injection or infusion
|Medicines & Healthcare Products Regulatory Agency (GB)
|MPI, EU: SmPC
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