Alectinib

Description

Alectinib is a highly selective and potent ALK and RET tyrosine kinase inhibitor. In preclinical studies, inhibition of ALK tyrosine kinase activity led to blockage of downstream signalling pathways including STAT 3 and PI3K/AKT and induction of tumour cell death (apoptosis).

Medicine classification

ATC Code
Title
Class
Alectinib
L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01E Protein kinase inhibitors → L01ED Anaplastic lymphoma kinase (ALK) inhibitors

Medicines

Drug
Countries

Australia Austria Cyprus France Hong Kong

Canada

Product monographs

Monograph
Type
Country

2D Molecule Structure

2D representation of molecule

Unique Ingredient Identifier (UNII)

LIJ4CT1Z3Y - ALECTINIB

CAS Registry Number

1256580-46-7 - alectinib

SNOMED-CT

716039000 - Alectinib (substance)