Alectinib

Active ingredient description

Alectinib is a highly selective and potent ALK and RET tyrosine kinase inhibitor. In preclinical studies, inhibition of ALK tyrosine kinase activity led to blockage of downstream signalling pathways including STAT 3 and PI3K/AKT and induction of tumour cell death (apoptosis).

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
L01ED03
Alectinib
L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01E Protein kinase inhibitors → L01ED Anaplastic lymphoma kinase (ALK) inhibitors
Discover more medicines within L01ED03

Medicines

Alectinib is the active ingredient of these drugs:

Drug
Countries
ALECENSA

Australia Austria Brazil Cyprus Finland

ALECENSARO

Canada

Product monographs

Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
ALECENSA Hard capsule
Summary of Product Characteristics (SPC)

Structural formula

Graphic representation of the active ingredient's molecular structure

Unique ingredient identifier (UNII)

LIJ4CT1Z3Y - ALECTINIB

CAS registry number

1256580-46-7 - alectinib

SNOMED-CT

716039000 - Alectinib (substance)

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