Alfentanil Other names: Alfentanyl

Chemical formula: C₂₁H₃₂N₆O₃  Molecular mass: 416.517 g/mol  PubChem compound: 51263

Therapeutic indications

Alfentanil is indicated for:

Analgesia, suppression of respiratory activity

Population group: only adults (18 - 65 years old)

It is indicated for analgesia and suppression of respiratory activity in mechanically ventilated patients on intensive care and to provide analgesic cover for painful manoeuvres. It will aid compliance with mechanical ventilation, and tolerance of the endotracheal tube. Intravenous bolus doses of alfentanil (0.5 mg/ml) may be used to provide additional pain relief during brief painful procedures such as physiotherapy, endotracheal suction, etc. Despite being mechanically ventilated, patients may be awake in the presence of adequate analgesia.

For this indication, competent medicine agencies globally authorize below treatments (click for details):


Alfentanil is contraindicated in the following cases:

Obstructive airway disease

at least one of
Respiratory obstruction
Decreased respiratory function

Monoamine oxidase inhibitors

MAO inhibitors


Labour operations



Effects on ability to drive and use machines

Effects on ability to drive and use machines

Get recommendations

Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

Ask the Reasoner

Related medicines

© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.