Alimemazine Other names: Trimeprazine

Chemical formula: C₁₈H₂₂N₂S  Molecular mass: 298.446 g/mol  PubChem compound: 5574

Active ingredient description

Alimemazine has a central sedative effect, comparable to that of chlorpromazine, but largely devoid of the latter’s antiadrenaline action. It has powerful antihistamine and anti-emetic actions. Alimemazine is used to treat neurosis, depression and anxiety of different origins. It prevents and relieves allergic conditions, which cause pruritus and urticaria by blocking histamine produced by the body during an allergic reaction. Alimemazine competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
R06AD01 Alimemazine R Respiratory system → R06 Antihistamines for systemic use → R06A Antihistamines for systemic use → R06AD Phenothiazine derivatives
Discover more medicines within R06AD01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
ALIMEMAZINE Film-coated tablets Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 84-96-8
DrugBank Drug: DB01246
KEGG Drug: D07125
PubChem Compound: 5574
RxNorm Ingredient: 10825
SNOMED-CT Concept: 387471006
Alimemazine (substance)
UNII Identifier: 76H78MJJ52


Alimemazine is an active ingredient of these brands:

Canada (CA)

France (FR)

Malta (MT)

Spain (ES)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.