Aliskiren and Hydrochlorothiazide

Active ingredient description

Combination of two antihypertensive active substances to control blood pressure in patients with essential hypertension. Aliskiren belongs to the class of direct renin inhibitors and hydrochlorothiazide to the class of thiazide diuretics. The combination of these substances with complementary mechanisms of action provides an additive antihypertensive effect, reducing blood pressure to a greater degree than either component alone.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
C09XA52 Aliskiren and hydrochlorothiazide C Cardiovascular system → C09 Agents acting on the renin-angiotensin system → C09X Other agents acting on the renin-angiotensin system → C09XA Renin-inhibitors
Discover more medicines within C09XA52

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
RASILEZ HCT Film-coated tablet European Medicines Agency (EU) MPI, EU: SmPC

External identifiers

RxNorm Ingredient: 802519

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