Allopurinol
Chemical formula: C₅H₄N₄O Molecular mass: 136.112 g/mol PubChem compound: 135401907
Active ingredient description
Allopurinol is a xanthine-oxidase inhibitor. Allopurinol and its main metabolite oxipurinol lower the level of uric acid in plasma and urine by inhibition of xanthine oxidase, the enzyme catalyzing the oxidation of hypoxanthine to xanthine and xanthine to uric acid.
Medicine classification
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC Group | Classification | |
|---|---|---|
| M04AA01 | Allopurinol | M Musculo-skeletal system → M04 Antigout preparations → M04A Antigout preparations → M04AA Preparations inhibiting uric acid production |
Product monographs
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Document | Type | Information Source | |
|---|---|---|---|
| ZYLORIC Tablet | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| ZYLOPRIM Tablet | MPI, US: SPL/Old | FDA, National Drug Code (US) |
Medicines
Allopurinol is an active ingredient of these brands:
Albania (AL)Australia (AU)Austria (AT)Brazil (BR)Canada (CA)Cyprus (CY)Ecuador (EC)Estonia (EE)Finland (FI)France (FR)Germany (DE)Hong Kong (HK)Ireland (IE)Israel (IL)Italy (IT)Japan (JP)Lithuania (LT)Malta (MT)Mexico (MX)Netherlands (NL)New Zealand (NZ)Poland (PL)Romania (RO)Singapore (SG)South Africa (ZA)Spain (ES)Tunisia (TN)Turkey (TR)United Kingdom (UK)United States (US)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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