Allopurinol

Active ingredient description

Allopurinol is a xanthine-oxidase inhibitor. Allopurinol and its main metabolite oxipurinol lower the level of uric acid in plasma and urine by inhibition of xanthine oxidase, the enzyme catalyzing the oxidation of hypoxanthine to xanthine and xanthine to uric acid.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Allopurinol
M Musculo-skeletal system → M04 Antigout preparations → M04A Antigout preparations → M04AA Preparations inhibiting uric acid production
Discover more medicines within M04AA01

Medicines

Allopurinol is the active ingredient of these drugs:

Drug
Countries

Netherlands

Hong Kong

Hong Kong

South Africa

Germany

New Zealand

Finland

Hong Kong

Hong Kong

Tunisia

Australia

Poland

Austria

Poland

United States

Cyprus

Ireland

Finland

Poland

Ecuador

Hong Kong

Germany

Hong Kong

Austria

Brazil

South Africa

Estonia Lithuania Poland

Australia

South Africa

Hong Kong

Austria South Africa Tunisia

South Africa

South Africa

Ecuador

Hong Kong

Hong Kong

Ireland

United Kingdom

South Africa

Austria Singapore

New Zealand

South Africa

Cyprus

Australia Canada South Africa United States

Austria Brazil Cyprus France Hong Kong

Allopurinol is also found within below combination drugs:

DUZALLO

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Structured Product Labeling (SPL)
US
Summary of Product Characteristics (SPC)
UK

Structural formula

Graphic representation of the active ingredient's molecular structure

Molecular mass: 136.112 g/mol

External identifiers

CAS Substance: 315-30-0
DrugBank Drug: DB00437
KEGG Drug: D00224
RxNorm Ingredient: 519
SNOMED-CT Concept: 387135004
Allopurinol (substance)
UNII Identifier: 63CZ7GJN5I
ALLOPURINOL