Chemical formula: Câ‚…Hâ‚„Nâ‚„O Molecular mass: 136.112 g/mol PubChem compound: 135401907
Allopurinol is a xanthine-oxidase inhibitor. Allopurinol and its main metabolite oxipurinol lower the level of uric acid in plasma and urine by inhibition of xanthine oxidase, the enzyme catalyzing the oxidation of hypoxanthine to xanthine and xanthine to uric acid.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| M04AA01 | Allopurinol | M Musculo-skeletal system → M04 Antigout preparations → M04A Antigout preparations → M04AA Preparations inhibiting uric acid production |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| ZYLOPRIM Tablet | FDA, National Drug Code (US) | MPI, US: SPL/Old | |
| ZYLORIC Tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Allopurinol is an active ingredient of these brands:
Albania (AL)Austria (AT)Canada (CA)France (FR)Hong Kong (HK)Israel (IL)Italy (IT)Japan (JP)Mexico (MX)Romania (RO)Spain (ES)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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