Active ingredient description

Almitrine is a diphenylmethylpiperazine derivative and respiratory stimulant that enhances respiration by acting as an agonist of peripheral chemoreceptors located on the carotid bodies. It is used in the treatment of chronic obstructive pulmonary disease. It is also reported to have a potentially beneficial effect in treating the noctural oxygen desaturation without impairing the quality of sleep.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
R Respiratory system → R07 Other respiratory system products → R07A Other respiratory system products → R07AB Respiratory stimulants
Discover more medicines within R07AB07

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₂₆H₂₉F₂N₇
Molecular mass: 477.552 g/mol

External identifiers

CAS Substance: 27469-53-0
DrugBank Drug: DB01430
KEGG Drug: D07126
PubChem Compound: 33887
RxNorm Ingredient: 528
SNOMED-CT Concept: 418600009
Almitrine (substance)
UNII Identifier: 9A1222NBG4


Almitrine is an active ingredient of these brands:

France (FR)

While we strive to include the brand names of medicines across all countries, our index remains incomplete. Therefore, it is possible that this medicine may also be marketed under different names in other countries.